Profil Klinik Infeksi Virus Dengue pada Bayi di Surabaya

Dominicus Husada, Catarina Rani, Dwiyanti Puspitasari, Widodo Darmowandowo, Parwati S. Basuki, Ismoedijanto Ismoedijanto

Sari


Latar belakang.Di Jawa Timur didapatkan peningkatan kasus infeksi virus dengue dari 4224 (2000)
menjadi 7180 (2004). Sekitar 5% di antaranya terjadi pada bayi <1 tahun. Bayi mempunyai karakter klinik
yang unik dan tidak banyak publikasi penelitian mengenai hal ini di Indonesia.
Tujuan.Mengetahui profil klinik bayi dengan infeksi virus dengue (IVD) yang dirawat di RSU Dr. Soetomo
Surabaya pada tahun 2010
Metode.Penelitian cross-sectional,menggunakan data dokumen medik bayi IVD yang dirawat di RSU Dr.
Soetomo Surabaya 1 Januari - 31 Desember 2010. Data yang dianalisis mencakup jenis kelamin, usia, hari
sakit saat diagnosis, suhu, batuk, diare, muntah, kejang, petekie, ensefalopati, hepatomegali, melena, dan
penurunan nafsu makan. Penelitian menggunakan derajat kemaknaan 95% (95% CI) dan p<0,05.
Hasil.Dari 82 bayi IVD, 53 digunakan sebagai sampel. Usia termuda bayi DBD 4 bulan, dengan modus pada
4-5 bulan (masing-masing 6 bayi). Kebocoran plasma umumnya terjadi pada hari keempat dan kelima. Rasio
laki:perempuan (PR 0,383), batuk (PR 0,191), ensefalopati (PR 4,5), hepatomegali (PR 2,818), dan melena
(PR 3,5) merupakan gejala dan tanda klinis yang signifikan yang membedakan DD dengan DBD.
Kesimpulan.Rerata usia dan kelompok usia terbanyak setara dengan beberapa penelitian lain. Batuk dan
jenis kelamin laki-laki lebih berhubungan dengan demam dengue, sedangkan ensefalopati, hepatomegali,
dan melena berhubungan dengan demam berdarah dengue.


Kata Kunci


bayi; infeksi virus dengue; profil klinik

Teks Lengkap:

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Referensi


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DOI: http://dx.doi.org/10.14238/sp13.6.2012.437-44

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