Faktor yang Memengaruhi Tumbuh Kejar Anak Pascaoperasi Koreksi Defek Septum Ventrikel

Marcella Trixie Kartika Novianingrum, Agus Priyatno, Rina Pratiwi

Sari


Latar belakang. Penyakit jantung bawaan (PJB) merupakan penyebab utama gagal tumbuh. Gangguan hemodinamik akibat defek septum ventrikel (DSV) memberikan gejala yang menggambarkan derajat kelainan jantung. Operasi koreksi memperbaiki gangguan hemodinamik dan pertumbuhan. Penelitian sebelumnya melaporkan bahwa perbaikan pertumbuhan setelah operasi DSV bersifat multifaktorial.
Tujuan. Untuk mengetahui faktor yang memengaruhi tumbuh kejar anak pascaoperasi koreksi DSV.
Metode. Penelitian kohort retrospektif pada 59 anak paska 6 bulan operasi koreksi DSV. Data mengenai jenis kelamin, ukuran defek, derajat hipertensi pulmonal, usia saat operasi, dan derajat gagal jantung dicatat. Data dianalisis menggunakan SPSS versi 26.
Hasil. Total sebanyak 59 data anak pascaoperasi koreksi DSV telah diperoleh dan 40 anak (67,8%) mencapai tumbuh kejar. Analisis bivariat menunjukkan bahwa ukuran defek, usia saat operasi, dan status gizi sebelum operasi memengaruhi tumbuh kejar paska operasi. Hasil tersebut dilanjutkan dengan analisis multivariat. Usia saat operasi merupakan faktor yang paling memengaruhi tumbuh kejar pascaoperasi DSV (p=0,038; RR 0,175; IK95%: 0,63-0,87). Nilai probabilitas anak usia 1-5 tahun untuk mencapai tumbuh kejar sebesar 0,204 (RR 1,09).
Kesimpulan. Ukuran defek, status gizi sebelum operasi, dan usia saat operasi memengaruhi tumbuh kejar pascaoperasi DSV. Usia saat operasi merupakan faktor yang paling memengaruhi tumbuh kejar pascaoperasi koreksi DSV.


Kata Kunci


defek septum ventrikel; operasi koreksi; tumbuh kejar

Teks Lengkap:

PDF

Referensi


Bouma BJ, Mulder BJ. Changing landscape of congenital heart disease. Circ Res. 2007;120:908-922.

Liu Y, Chen S, Zuhlke L. Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies. Int J Epidemiol 2019;48:455-463.

Li L, Li K, An C. Identification of risk factors affecting catch-up growth after infant congenital heart disease surgery: rationale and design of multicentre prospective cohort study in China. BMJ Open 2019;9:1-5.

Salih AF. Effects of ventricular septal defect on children’s growth pattern in Slemani Pediatric Teaching Hospital. Pediatr Ther 2015;5:1-5.

Murni IK, Djer MM, Yanuarso PB, Putra ST, Advani N, Rachmat J, dkk. Outcome of pediatric cardiac surgery and predictors of major complication in a developing country. Ann Pediatr Cardiol 2019;12:38-44.

Dai WS, Lin WH, Lin SH, Chen Q, Cao H. Postoperative health-related quality of life in children with congenital heart disease: a short-term follow-up study. J Cardiothoracic Surg 2023;18:1-6.

Arodiwe I, Chinawa J, Ujunwa F, Adiele D, Ukoha M, Obidike E. Nutritional status of congenital heart disease (CHD) patients: burden and determinant of malnutrition at university of Nigeria teaching hospital Ituku-Ozalla, Enugu. Pak J Med Sci 2015;31:1140-5.

Murni IK, Patmasari L, Wirawan MT, Arafuri N, Nurani N, Sativa ER, dkk. Outcome and factors associated with undernutrition among children with congenital heart disease. PLoS One 2023;18:1-10.

Nederend I, de Geus EJC, Blom NA, the Harkel ADJ. Long-term follow-up after ventricular septal defect repair in children: cardiac autonomic control, cardiac function and exercise capacity. Eur J Cardio-Thoracic Surg 2018;53:1082-8.

Banerji N, Sudhakar A, Balachandran R, Sunil GS, Kotayil BP, Kumar RK. Early weight trends after congenital heart surgery and their determinants. Cardiol Young 2020;30:89-94.

Fitria L, Caesa P, Joe J, Marwali EM. Did malnutrition affects post-operative somatic growth in pediatric patients undergoing surgical procedures for congenital heart disease? Pediatr Cardiol 2019;40:431-6.

Engelfriet P, Mulder BJ. Gender differences in adult congenital heart disease. Netherlands Hear J 2009;17:414-7.

Amel-Shahbaz S, Behjati-Ardakani M, Namayandeh SM, Vafaeenasab M, Andishmand A, Moghimi S, dkk. The epidemiological aspects of congenital heart disease in central and southern district of Iran. Adv Biomed Res 2014;3:1-5.

Vaidyanathan B, Nair SB, Sundaram KR, Babu UK, Shivaprakasha K, Gao SG, dkk. Malnutrition in children with congenital heart disease (CHD) determinants and short-term impact of corrective intervention. Indian Pediatr 2008;45:541-6.

Ploegstra MJ, Ivy DD, Wheeler JG. Growth in children with pulmonary arterial hypertension: A longitudinal retrospective multiregistry study. Lancet Respir Med 2016;4:281-90.

Kwant CT, Ruiter G, Noordegraaf AV. Malnutrition in pulmonary arterial hypertension. Curr Opin Pulm Med 2019;25:405-9.

Berger RMF, Beghetti M, Humpl T. Clinical features of paediatric pulmonary hypertension: A registry study. Lancet 2012;379:537-46. doi:10.1016/S0140-6736(11)61621-8

Nova R, Yosy DS. Association between size and type of ventricular septal defect and nutritional status in children. J Phys Conf Ser 2019;1246:1-5.

Djer MM, Osmardin E, Hegar B, Setyanto DB. Increased risk of recurrent acute respiratory infections in children with congenital heart disease: A prospective cohort study. Indones Biomed J 2020;12:355-60. doi:10.18585/INABJ.V12I4.1262.

Manso PH, Carmona F, Jácomo ADN, Bettiol H, Barbieri MA, Carlotti AP. Growth after ventricular septal defect repair: Does defect size matter? A 10-year experience. Acta Paediatr Int J Paediatr 2010;99:1356-6.




DOI: http://dx.doi.org/10.14238/sp24.6.2023.407-13

Refbacks

  • Saat ini tidak ada refbacks.


##submission.copyrightStatement##

##submission.license.cc.by-nc-sa4.footer##

Informasi Editorial:
Badan Penerbit Ikatan Dokter Anak Indonesia
Jl. Salemba I No 5, Jakarta 10430, Indonesia
Phone/Fax: +62-21-3912577
Email: editorial [at] saripediatri.org

Lisensi Creative Commons
Sari Pediatri diterbitkan oleh Badan Penerbit Ikatan Dokter Anak Indonesia
Ciptaan disebarluaskan di bawah Lisensi Creative Commons Atribusi-NonKomersial-BerbagiSerupa 4.0 Internasional.