Kelainan Kardiovaskular pada Anak dengan Berbagai Stadium Penyakit Ginjal Kronik
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Latar belakang. Penyakit kardiovaskular (PKV) merupakan penyebab orbiditas dan mortalitas tersering pada penyakit ginjal kronik (PGK) anak. Hipertrofi ventrikel kiri (LVH) dan disfungsi diastolik paling awal terlihat.
Tujuan. Mengetahui proporsi PKV pada PGK stadium 1, hubungan stadium PGK dengan LVH, dan disfungsi jantung.
Metode. Penelitian potong lintang analitik komparatif 26 subjek PGK anak di RS M Djamil Padang/ RS Hasan Sadikin Bandung. Dilakukan pemeriksaan urinalisis, hematologi rutin, ureum, kreatinin (eLFG), EKG, foto toraks, ekokardiografi. LVH dengan ekokardiografi bila left ventricular mass index (LVMI) >persentil 95 (38g/h2,7). Uji stastistik bermakna bila p<0,05.
Hasil. Rerata umur subjek 9,1(3,8) tahun. LVH pada 1 dari 3 subjek PGK stadium 1 dan 61,5% pada PGK seluruh stadium, terbanyak stadium 5. Tidak terdapat hubungan bermakna stadium PGK dengan LVH (p=0,055), disfungsi diastolik (p=0,937) dan disfungsi sistolik (p=0,929).
Kesimpulan. Pada PGK stadium 1 ditemukan LVH dan disfungsi diastolik. Tidak terdapat hubungan antara stadium PGK dengan LVH dan disfungsi jantung.
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DOI: http://dx.doi.org/10.14238/sp18.3.2016.220-5
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