Masalah Nutrisi pada Thalassemia

Luszy Arijanty, Sri S Nasar

Sari


Gangguan pertumbuhan pada thalassemia disebabkan oleh banyak faktor antara lain
faktor nutrisi. Gangguan pertumbuhan akibat kekurangan gizi dapat menyebabkan
perawakan pendek. Nutrisi yang adekuat sangat penting untuk pasien thalassemia sebagai
modalitas dalam pengobatan jangka panjang dan untuk mencegah gangguan gizi,
gangguan pertumbuhan, perkembangan pubertas dan defisiensi imun. Asupan nutrisi
yang dianjurkan pada thalassemia adalah tinggi kalori, protein, kalium, seng, vitamin
A,D, E, rendah besi sedangkan vitamin C harus dikurangi karena dapat meningkatkan
absorpsi besi. Suplementasi vitamin C dosis rendah diberikan bersamaan dengan
penggunaan desferoksamin untuk membantu meningkatkan pengeluaran besi.


Kata Kunci


thalassemia; nutrisi; tumbuh kembang

Teks Lengkap:

PDF

Referensi


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Fuchs GJ, Tienboon P, Khaled MA, Nimsakul S,

Linpisarn S, Faruque ASG. Nutritional support and

growth in thalassemia major. Archives of disease in childhood

; 76:509-12.

Nasar SS. Aspek gizi pada anak dengan perawakan

pendek. Dalam: Rukman Y, Batubara J, Tridjaja B,

penyunting. Masalah penyimpangan pertumbuhan

somatik pada anak dan remaja. Naskah lengkap PKBIKA

XXVIII. FKUI. 1993 16-17 Februari. Jakarta; Balai

Penerbit FKUI; 1993. h. 63-72.

Williams R, George EO, Wang W. Nutrition assessment

in children with sickle cell disease. J Assoc Acad Minor

Phys, Tenessee, USA,1997; 8:44-8.

Kuvibidila S, Warrier RP. Nutritional support of children

with sickle cell disease and thalassemia. Dalam:

Suskind RM, Suskind LL, penyunting. Textbook of pediatric

nutrition. Edisi ke-2. New York: Raven Press.

h. 425-36.

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Dalam: Walker WA, Hendricks KM, penyunting.

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Saunders Company. 1985. h. 52-62.

Almatsier S. Vitamin. Dalam: Prinsip dasar ilmu gizi.

Edisi pertama. Jakarta: PT. Gramedia Pustaka Utama,

h. 167-73.

Angelucci E, Brittenham GM, McLaren CE, Ripalti M,

Baronciani D, Giardini C, et all. Hepatic iron concentration

and total body iron stores in thalassemia major.

N Engl J med, 2000; 343:327-31.

Low iron diet for chronically-transfused patient. Didapat

dari http://www.thalassemia.com/transfusion/iron.shtm/.

Almatsier S. Mineral mikro. Dalam: Prinsip dasar ilmu

gizi. Edisi pertama. Jakarta: PT. Gramedia Pustaka

Utama, 2001. h. 249-257

King JC, Keen CL. Zinc. Dalam: Modern nutrition in

health and disease. Edisi ke-9. Philadelphia: Lippincott

Williams&Wilkins, 1998. h. 223-237.

NIH Clinical center. Zinc. Didapat dari: http://

www.nal.usda.gov/fnic/etext/000020.html.

Zemel BS, Kawchak DA, Fung EB, Stallings VA. Effect

of zinc supplementation on growth and body composition

in children with sickle cell disease. Am J of Clin

Nutr, 2002; 75:300-307.

Calcium and Thalassemia. Didapat dari http://

www.thalassemia.com/

The vitamin C/ferritin/iron connection. Didapat dari

http://www.thalassemia.com/

Combs GF. Vitamin D. Dalam: Combs GF, penyunting.

The Vitamins, fundamental aspects in nutrition and

health. San Diego, Academic press Inc. 1992. h. 151-781.

Brittenham GM, Griffith PM, Nienhuis AW. Efficacy

of deferoxamine in preventing complication of iron overloaded

in patients with thalassemia major. N Engl J med,

; 331:567-573.

Vitamin D and osteoporosis. Didapat dari http://

www.thalassemia.com/

Assessment of iron overload. Didapat dari http://

www.thalassemia.com/

Thalassaemia diet. Didapat dari http://www.altavista.com/




DOI: http://dx.doi.org/10.14238/sp5.1.2003.21-6

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