Masalah Nutrisi pada Thalassemia
Sari
Gangguan pertumbuhan pada thalassemia disebabkan oleh banyak faktor antara lain
faktor nutrisi. Gangguan pertumbuhan akibat kekurangan gizi dapat menyebabkan
perawakan pendek. Nutrisi yang adekuat sangat penting untuk pasien thalassemia sebagai
modalitas dalam pengobatan jangka panjang dan untuk mencegah gangguan gizi,
gangguan pertumbuhan, perkembangan pubertas dan defisiensi imun. Asupan nutrisi
yang dianjurkan pada thalassemia adalah tinggi kalori, protein, kalium, seng, vitamin
A,D, E, rendah besi sedangkan vitamin C harus dikurangi karena dapat meningkatkan
absorpsi besi. Suplementasi vitamin C dosis rendah diberikan bersamaan dengan
penggunaan desferoksamin untuk membantu meningkatkan pengeluaran besi.
Kata Kunci
Teks Lengkap:
PDFReferensi
Wahidiyat I. Penelitian thalassemia di Jakarta. Tesis.
Jakarta: Intermega, 1979.
De Sanctis V, Tangerini A, Lauriola L, Bellettati S. Growth
endocrine complications and reproduction in thalassemia
major. Didapat dari: http://www.mdconsult.com/
Spiliotis BE. b-thalassemia and normal growth: are they
compatible? Eur J of endocrinology, 1998, 139:143-4.
Nasar SS. Aspek gizi pada anak dengan perawakan
pendek. Dalam: Rukman Y, Batubara J, Tridjaja B,
penyunting. Masalah penyimpangan pertumbuhan
somatik pada anak dan remaja. Naskah lengkap PKBIKA
XXVIII. FKUI. 1993 16-17 Februari. Jakarta; Balai
Penerbit FKUI; 1993. h. 63-72.
Fuchs GJ, Tienboon P, Khaled MA, Nimsakul S,
Linpisarn S, Faruque ASG. Nutritional support and
growth in thalassemia major. Arch dis 1997; 76:509-12.
Tiosano D, Hochbrgz. Endocrine complication in patients
beta-thalassemia major. J Endocrinol Invest, Haifa,
Israel, 2001; 24:716-23.
Williams R, George EO, Wang W. Nutrition assessment
in children with sickle cell disease. J Assoc Acad Minor
Phys, Tenessee, USA,1997; 8:44-8.
Kuvibidila S, Warrier RP. Nutritional support of children
with sickle cell disease and thalassemia. Dalam:
Suskind RM, Suskind LL, penyunting. Textbook of pediatric
nutrition. Edisi ke-2. New York: Raven Press.
h. 425-36.
Vullo R, Modell B, Georganda E. Guidelines for clinical
management of thalassemia. Edisi ke-2. Nicosia: Thalassemia
International Federation, 1995. h. 26-53.
Almatsier S. Vitamin. Dalam: Prinsip dasar ilmu gizi.
Edisi pertama. Jakarta: PT. Gramedia Pustaka Utama,
h. 167-73.
Oliveri NF, De Silva S, Premawardena A, Sharma S, Viens
AM, Taylor CM, et all. Iron overloaded and iron chelating
therapy in hemoglobin E-beta thalassemia. J Pediatr
Hematol Oncol, Canada, 2000; 22:593-7.
Angelucci E, Brittenham GM, McLaren CE, Ripalti M,
Baronciani D, Giardini C, et all. Hepatic iron concentration
and total body iron stores in thalassemia major.
N Engl J med, 2000; 343:327-31.
Low iron diet for chronically-transfused patient. Didapat
dari http://www.thalassemia.com/transfusion/iron.shtm/.
Almatsier S. Mineral mikro. Dalam: Prinsip dasar ilmu
gizi. Edisi pertama. Jakarta: PT. Gramedia Pustaka
Utama, 2001. h. 249-57
King JC, Keen CL. Zinc. Dalam: Modern nutrition in
health and disease. Edisi ke-9. Philadelphia: Lippincott
Williams&Wilkins, 1998. h. 223-37.
NIH Clinical center. Zinc. Didapat dari: http://
www.nal.usda.gov/fnic/etext/000020.html.
Zemel BS, Kawchak DA, Fung EB, Stallings VA. Effect
of zinc supplementation on growth and body composition
in children with sickle cell disease. Am J of Clin
Nutr, 2002; 75:300-7.
Calcium and Thalassemia. Didapat dari http://
www.thalassemia.com/
The vitamin C/ferritin/iron connection. Didapat dari
http://www.thalassemia.com/
Brittenham GM, Griffith PM, Nienhuis AW. Efficacy
of deferoxamine in preventing complication of iron overloaded
in patients with thalassemia major. N Engl J med,
; 33:567-73.
Combs GF. Vitamin D. Dalam: Combs GF, penyunting.
The Vitamins, fundamental aspects in nutrition and
health. San Diego, Academic press Inc. 1992. h.151-78.
Vitamin D and osteoporosis. Didapat dari http://
www.thalassemia.com/
Assessment of iron overload. Didapat dari http://www.thalassemia.com/
Thalassaemia diet. Didapat dari http://www.altavista.com/
Weatherall DJ, Clegg JB. The b thalassemias. Dalam:
Gibbons R, Higgs DR, Old JM, Oliveri NF, Thein SL,
Wood WG, penyunting. The thalassemia syndromes.
Blackwell science Ltd, London, 2001. h. 287-344.
Mc Donagh KT, Nienhuis AW. The Thalassemias.
Dalam: Nathan DG, Oski FA, penyunting. Hematology
of infancy and childhood. Edisi ke-4. Philadelphia:
WB Saunders company,1993. h. 783-880.
Yaish HM. Thalassemia. eMedicine Journal, November
2001, Volume 2, Number 11. Didapat dari: http//
www.emedicine.com.
Vullo R, Modell B, Georganda E. Guidelines for clinical
management of thalassemia. Edisi ke-2. Nicosia: Thalassemia
International Federation, 1995. h. 26-53.
Oliveri NF, De Silva S, Premawardena A, Sharma S, Viens
AM, Taylor CM, et all. Iron overloaded and iron chelating
therapy in hemoglobin E-beta thalassemia. J Pediatr
Hematol Oncol, Canada, 2000; 22:593-7.
Fairbanks VF. Iron in medicine and nutrition. Dalam:
Modern nutrition in health and disease. Edisi ke-9. Philadelphia:
Lippincott Williams&Wilkins, 1998. h. 193-219.
Lauffer RB. Preventive measures for the maintenance of
low but adequate iron store. Dalam: Lauffer RB,
penyunting. Iron and human disease. Florida: CRC Press,
Inc. 1992. h. 460-74.
Tiosano D, Hochbrgz. Endocrine complication in patients
beta-thalassemia major. J Endocrinol Invest, Haifa,
Israel, 2001; 24:716-23.
WHO Working Group. Use and interpretation of anthropometric
indicators of nutritional status. Bulletin
of the World Health Organization, 1986, 64: 929-41.
Fuchs GJ, Tienboon P, Khaled MA, Nimsakul S,
Linpisarn S, Faruque ASG. Nutritional support and
growth in thalassemia major. Archives of disease in childhood
; 76:509-12.
Nasar SS. Aspek gizi pada anak dengan perawakan
pendek. Dalam: Rukman Y, Batubara J, Tridjaja B,
penyunting. Masalah penyimpangan pertumbuhan
somatik pada anak dan remaja. Naskah lengkap PKBIKA
XXVIII. FKUI. 1993 16-17 Februari. Jakarta; Balai
Penerbit FKUI; 1993. h. 63-72.
Williams R, George EO, Wang W. Nutrition assessment
in children with sickle cell disease. J Assoc Acad Minor
Phys, Tenessee, USA,1997; 8:44-8.
Kuvibidila S, Warrier RP. Nutritional support of children
with sickle cell disease and thalassemia. Dalam:
Suskind RM, Suskind LL, penyunting. Textbook of pediatric
nutrition. Edisi ke-2. New York: Raven Press.
h. 425-36.
Walker WA, Hendricks KM. Estimation of energy needs.
Dalam: Walker WA, Hendricks KM, penyunting.
Manual of pediatric nutrition. Philadelphia: WB
Saunders Company. 1985. h. 52-62.
Almatsier S. Vitamin. Dalam: Prinsip dasar ilmu gizi.
Edisi pertama. Jakarta: PT. Gramedia Pustaka Utama,
h. 167-73.
Angelucci E, Brittenham GM, McLaren CE, Ripalti M,
Baronciani D, Giardini C, et all. Hepatic iron concentration
and total body iron stores in thalassemia major.
N Engl J med, 2000; 343:327-31.
Low iron diet for chronically-transfused patient. Didapat
dari http://www.thalassemia.com/transfusion/iron.shtm/.
Almatsier S. Mineral mikro. Dalam: Prinsip dasar ilmu
gizi. Edisi pertama. Jakarta: PT. Gramedia Pustaka
Utama, 2001. h. 249-257
King JC, Keen CL. Zinc. Dalam: Modern nutrition in
health and disease. Edisi ke-9. Philadelphia: Lippincott
Williams&Wilkins, 1998. h. 223-237.
NIH Clinical center. Zinc. Didapat dari: http://
www.nal.usda.gov/fnic/etext/000020.html.
Zemel BS, Kawchak DA, Fung EB, Stallings VA. Effect
of zinc supplementation on growth and body composition
in children with sickle cell disease. Am J of Clin
Nutr, 2002; 75:300-307.
Calcium and Thalassemia. Didapat dari http://
www.thalassemia.com/
The vitamin C/ferritin/iron connection. Didapat dari
http://www.thalassemia.com/
Combs GF. Vitamin D. Dalam: Combs GF, penyunting.
The Vitamins, fundamental aspects in nutrition and
health. San Diego, Academic press Inc. 1992. h. 151-781.
Brittenham GM, Griffith PM, Nienhuis AW. Efficacy
of deferoxamine in preventing complication of iron overloaded
in patients with thalassemia major. N Engl J med,
; 331:567-573.
Vitamin D and osteoporosis. Didapat dari http://
www.thalassemia.com/
Assessment of iron overload. Didapat dari http://
www.thalassemia.com/
Thalassaemia diet. Didapat dari http://www.altavista.com/
DOI: http://dx.doi.org/10.14238/sp5.1.2003.21-6
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