Terapi Asiklovir pada Anak dengan Varisela Tanpa Penyulit
Sari
Varisela atau chickenpox atau yang dikenal dengan cacar air adalah infeksi primer virus zoster varicella (VZV)
yang umumnya menyerang anak dan merupakan penyakit yang sangat menular. Varisela pada anak tanpa
penyulit adalah ringan dan dapat sembuh sendiri. Pengobatan varisela bersifat simtomatik, namun dalam
praktek sehari-hari, masih banyak dokter yang memberikan asiklovir oral. Asiklovir sebagai terapi varisela
sudah lama digunakan termasuk pada anak sehat tanpa penyulit walaupun sampai saat ini masih kontroversial.
Berdasarkan hasil penelusuran didapatkan 8 artikel yang relevan yang dapat disimpulkan bahwa bila asiklovir
diberikan dalam 24 jam pertama timbulnya ruam, secara signifikan dapat mengurangi hari lamanya demam,
memperpendek lama sakit, mengurangi jumlah lesi, tapi tidak mengurangi komplikasi varisela (level of
evidence 1a). Namun asiklovir tidak dianjurkan diberikan secara rutin pada anak varisela tanpa penyulit,
karena ada pendapat bahwa kemungkinan terjadinya resistensi terhadap asiklovir dan menganggu imunitas
serta masalah biaya yang mahal.
Kata Kunci
Teks Lengkap:
PDFReferensi
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DOI: http://dx.doi.org/10.14238/sp11.6.2010.440-47
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