Epidemiologi Tuberkulosis

Cissy B. Kartasasmita

Sari


Tuberkulosis (TB) masih merupakan penyebab utama morbiditas dan mortalitas pada anak di dunia, namun
kurang mendapat prioritas dalam penanggulangannya. Data surveilans dan epidemiologi TB pada anak jarang
didapat. Hal ini disebabkan berbagai faktor antara lain sulitnya diagnosis TB anak, meningkatnya TB ekstra
paru pada anak, tidak adanya standar baku definisi kasus, dan prioritas yang kurang diberikan pada TB anak
di banding TB dewasa. Berbagai penelitian menunjukkan prevalensi TB anak tinggi, namun umumnya tanpa
konfirmasi pemeriksaan bakteri tahan asam (BTA) positif. Salah satu indikator untuk menilai situasi TB di
komunitas adalah dengan Annual Risk of Tuberculosis Infection (ARTI), adalah indeks epidemiologi yang
dipakai untuk evaluasi dan monitor keadaan tuberkulosis di suatu komunitas atau negara. Perbedaan angka
morbiditas dan mortalitas TB di berbagai negara dipengaruhi oleh beberapa faktor risiko, dibedakan antara
risiko infeksi TB dan sakit TB.


Kata Kunci


morbiditas; mortalitas; ART;, uji tuberkulin; faktor risiko

Teks Lengkap:

PDF

Referensi


World Health Organization (WHO). Guidance for

national tuberculosis programme on the management

of tuberculosis in children. WHO/HTM/2006.371.

World Health Organization (WHO). Childhood

tuberculosis and BCG vaccine: EPI Update Supplement

Geneva WHO, 1989.

Zar HJ, Hanslo D, Tannenbaum E. Aetiology and

outcome of pneumonia in human immunodeficiency

virus infected children hospitalized in South Africa. Acta

Paediatr 2001;90:119-25.

Madhi SA, Petersen K, Madhi A, Khoosal M, Klugman

KP. Increased disease burden and antibiot5ic resistance of

bacteria causing severe community-aquired lower respiratory

tract infections in human immunodeficiency virus type I

infected children. Clin Infect Dis 2000; 31:170-6.

Chintu C, Mudenda V, Lucas S. Lung diseases at necropsy

in African children dying from respiratory illnesses: a

descriptive necropsy study. Lancet 2002;360:985-90.

Jeena PM, Pillay T, Coovadia HM. Impact of HIV-1

co-infection on presentation and hospital-related

mortality in children with culture proven pulmonary

tuberculosis in Durban, South Africa. Int J Tuberc Lung

Dis 2002;6:672-8.

Madhi SA, Huebner RE, DoedensL, Aduc T, Wesley D,

Cooper PA. HIV-1 co-infection in children hospitalized

with tuberculosis in South Africa. Int J Tuberc Lung Dis

;4:448-54

Nelson LJ, Wells CD. Global epidemiology of childhood

tuberculosis. Int J Tuberc Lung Dis 2004;8:636-47.

Graham SM, Gie RP, Schaaf HS, Coulter JBS, Espinal

MA, Beyers N. Childhood tuberculosis: clinical research

needs. Int J Tuberc Lung Dis 2004;8:648-57.

Departemen Kesehatan RI. Rencana strategi nasional

penanggulangan tuberkulosis tahun 2002-2006. Jakarta:

Departemen Kesehatan RI; 2001.

Departemen Kesehatan RI. Pedoman nasional penanggula

ngan tuberkulosis. Cetakan ke-8. Jakarta: Departemen

Kesehatan Republik Indonesia; 2002.

Kochi A. The global tuberculosis situation and the

new control strategy of the world health organization.

Tubercle 1991;72:1-6.

Dolin PJ, Raviglione MC, Kochi A. Global tuberculosis

incidence and mortality during 1990 -2000. Bull World

Health Organ 1994;72:213-20.

Medical Research Council Tuberculosis and Chest

Disease Unit (MRCT-CDU). Tuberculosis in children:

a national survey of notifications in England and Wales

in 1983. Arch Dis of Child 1988;63:266-76.

Kartasasmita CB, Said M, Supriyatno B. Penapisan dan

pengobatan tuberkulosis pada anak sekolah dasar di

Majalaya, Kabupaten Bandung. MKB 2001;3:105-12.

Kartasasmita CB. Childhood tuberculosis in the

community. Disampaikan pada International Paediatric.

Respiratory and Allergy Congress; Prague, Czech

Republic 2001.

Rikesdas Indonesia tahun 2007. Laporan Hasil Riset

Kesehatan Dasar. Departemen Kesehatan Republik

Indonesia. Jakarta, 2008.

WHO 2004 WHO. TB/HIV a clinical manual. Edisi

ke-2. Geneva: World Health Organization; 2004.

WHO—SEARO. Tuberculosis control in the South-East

Asia Region. New Delhi, India: WE-- Regional Office

for South-East Asia; 2003.

Peter R D. Childhood tuberculosis: the hidden epidemic.

Int J Tuberc Lung Dis 2004;8:627-9.

Van Leth F, van der Wef MJ, Borgdorff MW. Prevalence

of tuberculous infection and incidence of tuberculosis; a

re-assessment of the Styblo rule. Bull WHO 2008;86:1-

Singh S, Chadha VK, Srivastava RK, Lakshminarayana,

Magesh V, Suganthi P, Umadevi G, dkk. Prevalence

and annual risk of tuberculosis infection among school

children in Bangalore rural district. NTI Bulletin

;42/3&4:68-73.

Gopi PG, Subramani R, Kolappan C, Prasad

VV, Narayanan PR. Estimation of annual risk of

tuberculosis infection among children irrespective of

BCG scar in the south zone of India. Indian J Tuberc

;53:7-11.

Gopi PG, Subramani R, Narayanan PR. Trend

in the prevalence of TB infection and ARTI after

implementation of a DOTS programme in south India.

Int J Tuberc Dis 2006;10:346-48.

Gopi PG, Prasad VV, Vasantha M, Subramani R,

Tholkappian AS, Sargunan D, Nayanan PR. Indian J

Tuberc 2008;55:157-61.

Kumar S, Radhakrishna, Chadha VK, Jeetendra R, Kumar

P, Chauhan LS, Srivastava R, Umadevi, Kirankumar

R. Prevalence of tuberculosis infection among school

children in Kerala. Indian J Tuberc 2009;56:10-16.

Bachtiar A, Miko TY, Machmud R, Besral, Yudarini,

Basri C, Mehta F, Chadha VK, Loprang F, Manissero

D, Palupi KR, Jitendra R. Annual risk of tuberculosis

infection in West Sumatra Province, Indonesia.Int J

Tuberc Dis 2008;12:255-61.

Lienhardt C, Fielding K, Sillah J, Tunkara A, Donkor S,

Manner K, Warndoff D, McAdam KP, Bennett S. Risk

factors for Tuberculosis infection in Sub-Sahara Africa.

Am J Respir Crit Care Med 2003;168:448-55.




DOI: http://dx.doi.org/10.14238/sp11.2.2009.124-9

Refbacks

  • Saat ini tidak ada refbacks.


##submission.copyrightStatement##

##submission.license.cc.by-nc-sa4.footer##

Informasi Editorial:
Badan Penerbit Ikatan Dokter Anak Indonesia
Jl. Salemba I No 5, Jakarta 10430, Indonesia
Phone/Fax: +62-21-3912577
Email: editorial [at] saripediatri.org

Lisensi Creative Commons
Sari Pediatri diterbitkan oleh Badan Penerbit Ikatan Dokter Anak Indonesia
Ciptaan disebarluaskan di bawah Lisensi Creative Commons Atribusi-NonKomersial-BerbagiSerupa 4.0 Internasional.