Telaah Perbandingan Panduan Klinis Sindrom Nefrotik Idiopatik Resisten Steroid pada Anak
Sari
Latar belakang. Sebagai salah satu penyakit ginjal anak tersering di dunia, sindrom nefrotik dapat dibedakan menjadi sensitif dan resisten steroid. Penelitian dan tata laksana sindrom nefrotik resisten steroid pada anak terus berkembang. Panduan klinis yang digunakan seringkali berbeda dan bervariasi antar fasilitas kesehatan ataupun negara di dunia.
Tujuan. Membandingkan panduan klinis sindrom nefrotik idiopatik resisten steroid pada anak.
Metode. Kami menentukan topik dan lingkup bahasan yang akan dibahas. Sesudah itu, dilakukan telaah dan perbandingan terhadap empat panduan klinis dari Ikatan Dokter Anak Indonesia tahun 2012, Kidney Disease: Improving Global Outcomes tahun 2021, Indian Society of Pediatric Nephrology tahun 2021, dan International Pediatric Nephrology Association tahun 2020. Empat lingkup bahasan kajian antara lain diagnosis, pemeriksaan penunjang, batasan kriteria, dan terapi.
Hasil. Didapatkan beberapa perbedaan mendasar yang ditemukan, antara lain, adanya periode konfirmasi, beberapa istilah baru, anjuran pemeriksaan genetik, serta pilihan utama terapi imunosupresan.
Kesimpulan. Sesudah menelaah panduan klinis sindrom nefrotik idiopatik resisten steroid dari Ikatan Dokter Anak Indonesia tahun 2012 dan panduan klinis baru lainnya, ditemukan beberapa pebedaan dasar. Oleh karena itu, diperlukan pembaharuan konsensus sindrom nefrotik resisten steroid yang disesuaikan dengan bukti ilmiah terbaru serta ketersediaan fasilitas kesehatan dan obat-obatan di Indonesia.
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DOI: http://dx.doi.org/10.14238/sp25.3.2023.137-46
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