Pengaruh Asupan Nutrisi pada Bayi Prematur dengan Pertumbuhan Ekstrauteri Terhambat di Rumah Sakit Anak Bunda Harapan Kita

Toto Wisnu Hendrarto, Wida Ayu Nurahma, Marpauling Marpauling, Karina Karina

Sari


Latar belakang. Tantangan tatalaksana bayi prematur adalah terjadinya pertumbuhan ekstra uteri terhambat karena kecukupan nutrisi tidak sesuai dengan kebutuhan pertumbuhannya.
Tujuan. Mengetahui distribusi terjadinya PEUT menurut asupan jenis nutrisinya.
Metode. Penelitian deskriptif retrospektif dari rekam medik bayi prematur dirawat di Rumah Sakit Anak Bunda Harapan Kita pada Juli 2018 – Juli 2019.
Hasil. Penelitian ini melibatkan 128 bayi prematur. Jenis asupan nutrisi yang diterima adalah ASI, ASI dengan fortifikasi human milk fortifier, ASI dengan susu formula prematur dan susu formula prematur saja. Bayi prematur yang mengalami PEUT berjumlah 55 (43%). Risiko terjadinya PEUT 1,08 dan 1,78 berturut-turut pada ASI dibandingkan dengan susu formula serta ASI dibandingkan dengan ASI ditambah HMF. Percepatan pertumbuhan tertinggi pada kelompok PEUT yang mendapat ASI dengan fortifikasi HMF (14 gram/kgBB/hari), terendah pada kelompok susu formula prematur (4,6 gram/kgBB/hari). Percepatan kenaikan berat badan hampir sama pada semua bayi prematur dalam kelompok pertumbuhan normal (11,5 – 13,7 gram/kgBB/hari).
Kesimpulan. Air susu ibu adalah pilihan terbaik dalam pemberian introduksi nutrisi enteral pada periode kritis perawatan bayi prematur. Jenis nutrisi enteral pada periode pertumbuhan disesuaikan dengan kecukupan kebutuhan masing-masing bayi prematur.


Kata Kunci


bayi prematur; pertumbuhan ekstra uteri terhambat; jenis nutrisi

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Referensi


Ehrenkranz RA, Das A, Wrage LA, dkk. Early nutrition mediates the influence of severity of illness on `extremely low birth weight infants. Pediatr Res 2011;69:522-9.

Belfort MB, Ehrenkranz RA. Neurodevelopmental outcomes and nutritional strategies in very low birth weight infants. Seminars in Fetal & Neonatal Med 2016:1-7.

Morgan J, Bombell S, McGuire W. Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants (Review). Cochrane Database Syst Rev 2013:1-29.

Ehrenkranz RA. Early, Aggressive nutritional management for very low birth weight infants: what is the evidence? Seminars in Perinatol 2007;31:48-55.

Prince A, Groh-Wargo S. Nutrition management for the promotion of growth in very low birth weight premature infants. Nutr Clin Pract 2013;28:559-668.

Tozzi MG, Moscuzza F, Michelucci A, dkk. Extra uterine growth restriction (EUGR) in preterm infants: growth patterns, nutrition, and epigenetic markers. A pilot study. Frontiers in Pediatr 2018;6:1-9.

Kumar RK, Singhal A, Vaidya U, Banerjee S, Anwar F, Rao S. Optimizing nutrition in preterm low birth weight infants : consensus summary. Frontiers in Nutr 2017;4:1-9.

Eibensteiner F, Auer-Hackenberg L, Jilma B, Thanhaeuser M, Wald M, Haiden N. Growth, feeding tolerance and metabolism in extreme preterm infants under an exclusive human milk diet. Nutrients 2019;11:1-15.

Lok KY, Chau PH, Fan HSL, dkk. Increase in weight in low birth weight and very low birth weight infants fed fortified breast milk versus formula milk: a retrospective cohort study. Nutrients 2017;9:1-9.

Quigley M, Embleton ND, McGuire W. Formula versus donor breastmilk for feeding preterm or low birth weight infants (Review). Cochrane Database Syst Rev 2018:1-93.

Pampanini V, Boiani A, Marchis CD, dkk. Preterm infants with severe extrauterine growth retardation (EUGR) are at high risk of growth impairment during childhood. Eur J Pediatr 2015;174:33-41.

Su BH. Optimizing Nutrition in Preterm Infants. Pediatr Neonatol 2014:5-13.

Clark RH, Thomas P, Peabody J. Extrauterine growth restriction remains a serious problem in prematurely born neonates. Pediatrics 2003;111:986–90.

Gao XY, Feng L, Xu J, Pan XN. Follow-up observation of catch-up growth of preterm infants after discharge and risk factors for extrauterine growth retardation. CJCP 2018;20:438-48.

Lin Z, Green RS, Chen S, dkk. Quantification of EUGR as a measure of the quality of nutritional care of premature infants. PLoS ONE 2015;10:1-10.

Lee SM, Kim N, Namgung R, Park M, Park K, Jeon J. Prediction of Postnatal Growth Failure among Very Low Birth Weight Infants. Scientific Reports 2018;8:1-8.

Simon L, Hanf M, Frondas-Chauty A, dkk. Neonatal growth velocity of preterm infants: The weight Z-score change versus Patel exponential model. PLoS ONE 2019;14:1-11.

Paudel L, Kalakheti B, Sharma K. Prevalence and outcome of preterm neonates admitted to neonatal unit of a tertiary care center in Western Nepal. JLumbini Med Col 2018;6(2):1-6.

Agostoni C, Braegger C, Decsi T, dkk. Role of dietary factors and food habits in the development of childhood obesity: a commentary by the ESPGHAN committee on nutrition. JPGN 2011;52:662–9.

Brown JVE, Embleton ND, Harding JE, McGuire W. Multi-nutrient fortification of humanmilk for preterm infants (Review). Cochrane Database Syst Rev 2016:1-55.

Amissah EA, Brown J, Harding JE. Protein supplementation of human milk for promoting growth in preterm infants. Cochrane Database Syst Rev 2018:1-3.

Arslanoglu S, Boquien C-Y, King C, dkk. Fortification of human milk for preterm infants: update and recommendations of the European Milk Bank Association (EMBA) Working group on human milk fortification. Frontiers in Pediatrics 2019;7:1-14.

Liu T-T, Dang D, Lv X-M, Wang T-F, Du J-F, Wu H. Human milk fortifier with high versus standard protein content for promoting growth of preterm infants: A meta-analysis. J Int Med Res 2015;43:279-89.

Kemp J, Wenhold F. Human milk fortification strategies for improved in-hospital growth of preterm infants. South Afr J Clin Nutr 2016;29:157-64.

Young L, Embleton N, McGuire W. Nutrient-enriched formula versus standard formula for preterm infants following hospital discharge (Review). Cochrane Database Syst Rev 2016:1-61.

Karagol BS, Zenciroglu A, Okumus N, Polin RA. Randomized controlled trial of slow vs rapid enteral feeding advancements on the clinical outcomes of preterm infants with birth weight 750–1250 g. PEN J Parenter Enteral Nutr 2013;37:223-8.

Rayyis SF, Ambalavanan N, Wright L, Carlo WA. Randomized trial of “slow” versus “fast” feed advancements on the incidence of necrotizing enterocolitis in very low birth weight infants. J Pediatr 1999;134:293-7.

Schanler RJ, Shulman RJ, Lau C. Feeding Strategies for premature infants: beneficial outcomes of feeding fortified human milk versus preterm formula. Pediatrics 1999;103:1150-7.

Wu Y, Zhong XY, Jiang J, Gong H. Prospective and controlled study on effect of fortified human milk feeding on infants with extremely and very low birth weight during hospital stay. J Peking University 2016;8:143-7.

Henriksen C, Westerberg AC, Rønnestad A, dkk. Growth and nutrient intake among very-low-birth-weight infants fed fortified human milk during hospitalisation. British J Nutr 2009;102:1179–86.

Lemons JA, Moye L, Hall D, Simmons M. Differences in the composition of preterm and term human milk during early lactation. Pediatr Res 1982;16:113-7.

Li G, Zhang A, Lin H, dkk. Analysis of nutritional status of preterm infants at early life. Dig Med Res 2016;2:1-6.

Nicolas E. Embleton NPaRJC. Postnatal malnutrition and growth retardation: an inevitable consequence of current recommendations in preterm infants? Pediatrics 2001;107:270–3.

Olsen IE, Richardson DK, Schmid CH, Ausman LM, Dwye JT. Intersite differences in weight growth velocity of extremely premature infants. Pediatrics 2002;110:1125–32.

Henderson G, Fahey T, McGuire W. Nutrient-enriched formula milk versus human breast milk for preterm infants following hospital discharge (Review). Cochrane Database Syst Rev 2007:1-11.




DOI: http://dx.doi.org/10.14238/sp22.3.2020.169-75

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