Hubungan Mikroflora Usus pada Bayi Baru Lahir dengan Jenis Persalinan

Mira Febriani Hontong, Sarah M Warouw, Jeanette I. Ch. Manoppo, Praevilia Salendu

Sari


Latar belakang.Mikroflora saluran cerna pada awal kehidupan berperan penting untuk respon imun dan dapat dipengaruhi oleh jenis persalinan.
Tujuan. Mengetahui hubungan antara jumlah koloni mikroflora usus Bifidobacterium, Lactobacillus, Clostridium, pada bayi baru lahir dengan
jenis persalinan.
Metode. Penelitian observasional analitik dengan pendekatan potong lintang terhadap semua bayi aterm sehat yang lahir pervaginam dan seksio
sesarea dari bulan Oktober 2013–November 2013 di Divisi Perinatologi Departemen Ilmu Kesehatan Anak (IKA) RSUP Prof. Dr. R.D. Kandou,
Manado. Dilakukan pemeriksaan tinja dengan quantitative realtime polymerase chain reaction (PCR-RT) untuk mendeteksi kolonisasi mikroflora
Bifidobacterium, Lactobacillus, dan Clostridium. Pengolahan data dengan uji Mann-Whitney.
Hasil. Dua puluh lima subjek bayi lahir pervaginam dan 25 subjek bayi lahir secara seksio. Terdapat perbedaan bermakna jumlah koloni Bifidobacterium
pada persalinan pervaginam (median 2,19 x 109 CFU/g) dibandingkan seksio sesarea (median 1,55 x 109 CFU/g) (p<0,001). Median koloni Lactobacillus
pada persalinan pervaginam 3,40 x 109 CFU/g tidak berbeda bermakna dengan seksio sesarea 3,51 x 109 CFU/g (p=0,362). Median koloni Clostridium
pada persalinan pervaginam 1,12x 109 CFU/g juga tidak berbeda bermakna dengan seksio sesarea 1,04 x 109 CFU/g (p=0,961).
Kesimpulan. Persalinan pervaginam kolonisasi mikroflora Bifidobacterium lebih tinggi dibandingkan dengan seksio sesarea. Tidak terdapat perbedaan
bermakna kolonisasi mikroflora Lactobacillus dan Clostridium pada persalinan pervaginam dan seksio sesarea


Kata Kunci


bifidobacterium; lactobacillus; clostridium; mikroflora usus

Teks Lengkap:

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Referensi


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DOI: http://dx.doi.org/10.14238/sp17.1.2015.25-8

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